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Using this platform, they demonstrated that Aurora kinase inhibitors (AURKi) induce senescence in diffuse-type gastric cancer (DGC) cells and promote secretion of MCP-1/CCL2, which remodels the immune microenvironment and skews macrophages toward an M2 phenotype, contributing to therapeutic resistance
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However, competitions such as Critical Assessment of Functional Annotation [21] have not yet found a solution for de novo function prediction from sequence
Psychiatry 34 ForsterN
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