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For example, a tri-functional copper-based MOF nanozyme developed by Dong et al.not only generates ROS but also modulates the redox environment, overcoming chemotherapy resistance in CRC and providing a new therapeutic strategy for future clinical applications [101]

PMID: 39444151

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Mice lived in a cycle of 12 h of light and 12 h of darkness

Thirdly, an unbalanced redox state generates a pro-oxidative microenvironment around follicles, negatively impacting oocyte quality, and sperm and embryo viability