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Should I inject locally or systemically
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These are typically dose-dependent and reversible with dose reduction or cycle discontinuation
Vitamin B12 injection is currently licensed for use in maintenance therapy for pernicious anaemia every 2 3 months depending on the type of pernicious anaemia
Pan et al, in a in vivo study performed with transgenic mice, have shown that chronic treatment with benfotiamine, a thiamine derivate with better bioavailability, enhanced the spatial memory and reduced both amyloid plaque numbers and phosphorylated tau levels, suggesting that this thiamine derivative may be useful in clinical Alzheimers disease treatment, although others thiamine derivatives do not showed the same results ( Table 2 )
In the evaluation of RCT quality, 3 studies scored two points, indicating low-quality study and high risk of bias
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