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N., Hutabarat, E

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82 Microstructural analyses showed trabecular thinning, increased separation and heterogeneitychanges most marked in postmenopausal subjects

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The addition of glucagon receptor agonism raises theoretical considerations around heart rate elevation , and Phase 2 data did show modest increases in resting heart rate in some participants a finding that will require careful monitoring in Phase 3 cardiovascular outcome trials

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