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This work has led to the suggestion that sulfated neurosteroids must be transported from the periphery into the CNS, but this hypothesis has not been validated (186)

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Follow-up showed no developmental concerns

A Systematic review of the incidence, prevalence, costs, and activity and work limitations of amputation, osteoarthritis, rheumatoid arthritis, back pain, multiple sclerosis, spinal cord injury, stroke, and traumatic brain injury in the United States: a 2019 update