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In TNBC, SLC38A2 plays a crucial role in promoting glutamine dependency and conferring resistance to oxidative stress [71]
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The construction of the functionalized piperidinone scaffold in a one-pot manner was facilitated by a novel three-component cascade coupling with a chiral nitro diet, which was easily obtained through a substantially enantioselective Michael addition of dimethyl malonate to nitrostyrene
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For laboratory handling it is typically reconstituted in bacteriostatic water