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Improved glycaemic control is perhaps the most significant contributor

SUSTAIN 1: Showed significant HbA1c reduction and weight loss compared to placebo in patients with type 2 diabetes and BMI 25 kg/m [7]

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This FDA approval offers an additional tool to address this serious, chronic, progressive disease. In addition to the usual safety information for this class of medications, the product label suggests discontinuing Wegovy before attempting pregnancy (for both females and males), and stopping if an unplanned pregnancy occurs

5 and 6) can pass through epithelial cell layers with a transcellular absorption mechanism with the help of permeation enhancers like salcaprozate sodium (SNAC, see Fig