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281 , E155E161 (2001)
Moreover, the SURPASS programme demonstrated that tirzepatide 15 mg is more efficacious in glycaemic control for people with T2D compared to insulin therapies as well as GLP-1 mono-agonists including semaglutide 1 mg and dulaglutide 1.5 mg
150,152,153 Activation of the GLP-1R can enhance insulin secretion, reduce glucagon secretion, delay gastric emptying, 154 and suppress appetite
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