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Head-to-head finding: Tirzepatide produced greater average weight loss than semaglutide in the SURMOUNT-5 study population
Overall, at week 88, participants with 75% or more weight regain after tirzepatide withdrawal reversed cardiometabolic parameters to baseline (week 0) values, the team write, although they note those with up to 50% weight regain still showed improvements in these areas compared with the start of the study
It may also increase growth factors, which are necessary for any tissue repair
Stevens-Lapsley JE, Ye F, Liu M, et al
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