Interactions via delayed gastric emptying: Retatrutide, like other incretin-class agents, slows gastric emptying, which may alter the absorption of concomitant oral medicines
Supplementation: Begin magnesium glycinate 200 mg at bedtime, B-complex vitamin with breakfast, and vitamin D3 2,000 IU daily
This glucose-dependent action helps prevent dangerous drops in blood sugar
Endocrinology 2000
They also reduce prostaglandins and nitric oxide, which are involved in inflammatory reactions, by modifying the activity of cyclooxygenase (COX-2) and inducible nitric oxide synthase (iNOS)
Additionally, both diets led to a decrease in T3 levels from baseline, but the high-fat diet resulted in lower T3 levels [18]