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Also, an analysis of blood chemistries of smokers supplementing with beta-carotene revealed that the combination of beta-carotene and cigarette smoke may increase cancer cell growth by promoting certain detoxification pathways and raising the levels of specific metabolites (Mondul 2013)

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George SM, Harrison DA, Welch CA, Nolan KM, Friedmann PS (2008) Dermatological conditions in intensive care: a secondary analysis of the Intensive Care National Audit and Research Centre (ICNARC) Case Mix Programme database