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As a GLP-1/GIP/glucagon receptor agonist, it may theoretically delay gastric emptying, which is a class-related effect that could affect the absorption of orally administered medicines
The SURMOUNT-1 trial showed up to 20.9% body weight reduction with 15 mg tirzepatide over 72 weeks, compared to roughly 15% with semaglutide in the STEP trials
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