When applying the treatment policy estimand, researchers reported superior weight loss of 15.1% among those treated with oral semaglutide 50 mg compared to a reduction of 2.4% in the placebo group
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However, the study found no correlation between Akkermansia and hyperglycemia, fasting blood glucose, and hypertension
For Salkin, the takeaway is not fear or alarm
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Tambin se report un aumento modesto de la frecuencia cardaca dependiente de dosis (pico alrededor de 24 semanas, con tendencia a disminuir hacia 48 semanas)