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Injections achieve close to 100%, resulting in meaningful tissue concentrations rather than minimal absorption
However, the slowing of gastric emptying and effects on gastrointestinal motility mean that digestive side effects are among the most commonly reported adverse reactions with this class of medication
Reviews, editorials, animal studies, and studies based solely on spontaneous pharmacovigilance reports were excluded when pooling data for scientific analyses
The potential for drug interactions should not be overlooked
Metabolic changes during treatment with valproate in humans: implication for untoward weight gain
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