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The daily dose of TAD 600 usually recommended for patients receiving chemotherapy with cisplatin and related compounds is 1.5 g/m (equivalent to 2.5 g) by slow intravenous infusion

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The disease is particularly prevalent in the Faroe Islands, an archipelago between Scotland and Iceland with little genetic variation

This has important implications for clinical practice and health policy, particularly given cardiovascular disease is the leading cause of death in the UK

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