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Pharmacological activation of Nrf2 enhances the expression of cytoprotective genes, conferring resistance against oxidative injury and fibrogenesis in DKD models (242)

Lower glutathione levels seem to go hand-in-hand with poorer health

The American Diabetes Associations position that metformin should remain the first-line treatment for most type 2 diabetes cases is partly driven by this cost advantage at roughly $120 per year versus over $11,000 annually for Rybelsus, metformins modest efficacy is justified for 90% of people starting type 2 diabetes treatment

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doi:10.3390/nu2030299 de Jager J, et al

Alternative Tip : If you want an adult beverage, stick to sparkling water with a slice of lemon or lime, unsweetened tea, or a small serving of wine