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The main sources of ROS under physiological conditions include the mitochondrial respiratory chain, peroxisomes, NADPH oxidase (NOX), and lipoxygenase (ALOX), and additional ROS-producing enzymes, such as cyclooxygenases (COXs) and cytochrome p450s (CYPs) [12, 13]
Melanocortin Pathways in Sexual Function
PMCID: PMC8996222
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TMAO levels rise with age-related cognitive dysfunction, inducing mitochondrial dysfunction, oxidative stress, neuronal senescence, and synaptic damage
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