Sugar Crash Effects and How to Fix Them
The LEADER trial demonstrated that liraglutide reduced the risk of cardiovascular death by 22%, cut death from any cause by 15%, and reduced major adverse cardiovascular events (heart attack, stroke, or cardiovascular death) by 13%
Retatrutide promises big weight loss, but safety remains a question
Nat Med 8(7):738742 Ggebakan , Andres J, Biedasek K et al (2012) Glucose-dependent insulinotropic polypeptide reduces fat-specific expression and activity of 11-hydroxysteroid dehydrogenase type 1 and inhibits release of free fatty acids
Retatrutide's glucagon activity can also transiently affect heart rate and glycemic dynamics variables that become harder to interpret when a second agonist is layered on
For tirzepatide users who also use B12-containing compounded products, the storage principles are identical