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The reactive oxygen species then donates one electron to a glutathione molecule, completing the oxidation-reduction reaction and rendering it unable to perform oxidative damage to the cell

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POTS is characterized by a heart rate increase of at least 30 beats per minute when you go from sitting or lying down to a standing position

Rapid titration or initiating at higher doses increases the chance of early nausea because compensatory physiological adaptation is outpaced

Maximum weight loss: 24.2% at 12 mg/week (Jastreboff et al., 2023)

Theophylline dosage adjustments may be needed with thyroid hormone replacement