Here is what has occurred and what patients may expect in the coming months based on manufacturer announcements and regulatory filings: December 22, 2025: FDA approved oral Wegovy (semaglutide 25 mg), the first oral GLP-1 for weight loss
I have thousands of patient on these medications
While other GH peptides work by raising growth hormone (which then raises IGF-1), this one skips the middleman and delivers IGF-1 directly
AMPK activation = increased glucose uptake and fat oxidation Downregulates anabolic processes that consume ATP Promotes mitochondrial biogenesis and cellular resilience MOTSc functions as a mitochondrial-encoded hormone that enhances metabolic flexibility and insulin sensitivity. Lee et al., Cell Metabolism Natural Expression and Peptide Supplementation Your body naturally produces MOTSc, particularly during fasting or exercise
If you are, thats an indication that you need to make changes to your thyroid treatment regimen
Protein phosphorylation mediated by kinases and phosphatases play a key role in cellular signaling that regulates many physiological and pathological processes, and consequently, the modification of cysteine regulates its activities