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GLP-1 receptor agonists like semaglutide have emerged as powerful weight loss tools, but patients with active or severe ulcerative colitis need specialized guidance to prevent flares

In terms of DPN, there is growing evidence that GLP-1 RAs provide neuroprotective effects, which may help limit or slow the progression of neuropathy in some patients

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Cardiovascular Protection Certain GLP-1 medications have been shown to reduce the risk of: Heart attack Stroke Cardiovascular death particularly in people with Type 2 diabetes and established cardiovascular disease

Lipase and amylase levels may become elevated in some patients, though routine monitoring in asymptomatic patients is not recommended

Refrigeration: Is It Necessary