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Here, we will cover some of the key considerations and findings related to prolonged use of GLP-1 receptor agonists

GLP-1 agonist escalation The escalation schedule for semaglutide and similar compounds exists specifically to minimize gastrointestinal side effects

Weekly dosage schedule Starting dose: 0.25 mg weekly for first 4 weeks Titration phase: 0.5 mg weekly for 4 weeks and then, if tolerated, 1 mg weekly for 4 weeks Maintenance dose for long-term weight management: 1.7 mg once weekly for 4 weeks and then, if tolerated, 2.4 mg once weekly (maximum dose) Dosing considerations If you do not tolerate dose escalation, consult with your healthcare provider and consider delaying the dose escalation for at least 4 weeks

Geltink, R

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This content should not be interpreted as medical advice, a recommendation for treatment, or evidence of established clinical effectiveness