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Protocol 1: Core perimenopause support (all women) Goal: Address fundamental hormonal and metabolic changes Foundation stack: CJC-1295: 150-200mcg before bed Ipamorelin: 150-200mcg before bed BPC-157: 250mcg twice daily Selank: 300mcg intranasal, 1-2x daily as needed Why this stack: CJC + Ipamorelin: Restore GH, metabolism, sleep, energy BPC-157: Heal gut, reduce inflammation Selank: Manage mood swings and anxiety Schedule: Morning: BPC-157 250mcg, Selank 300mcg (if using) Evening: BPC-157 250mcg Before bed: CJC-1295 + Ipamorelin 150-200mcg each Duration: 6-12 months minimum (throughout perimenopause transition) Expected benefits: Better energy and vitality Improved sleep quality Maintained metabolism Reduced inflammation Stable mood Overall improved quality of life Cost: $300-450/month See our peptide stacks guide , can you cycle different peptides , and peptide cycle planning guide

Why some people experience mood changes On the other hand, some users report increased anxiety, irritability, or low mood during GLP1 treatment

This shows fat mass, visceral fat, skeletal muscle, and body water, which all inform medication choice and lifestyle planning

Chen H, Elhawi M, Tarbox M: The therapeutic effects of semaglutide in congenital linear scleroderma

Moreover, the strong effects observed in animal studies have not always translated to humans (Forssten et al., 2022

Figure 1 Ferroptosis, first characterized by the Brent R