I found no completed, controlled human trial with published results in people
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MOTS-C: A mitochondrial-derived peptide that supports metabolic health and physical endurance
Tesamorelin, a more potent GHRH analog, has Phase 3 human trial data for visceral fat reduction in HIV-associated lipodystrophy, which provides some mechanistic validation for the class
Yet emerging research reveals a complementary hormone equally important to appetite regulation and metabolic control: GIP (glucose-dependent insulinotropic polypeptide), formerly known as glucose-dependent insulinotropic peptide
Lets unpack the science, the results, and what it means for your joints