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Ruscogenin treatment significantly relieved FA-induced AKI, improved kidney function indicators, restored the expression of SLC7A11 and HO-1 and suppressed the FA-induced upregulation of Rev-erb/
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i , Mutation of C160 inhibited the labeling of HA-ZDHHC7 by B4 (10 M)
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We need glutathione to move these toxic substances through the detoxification process and into elimination pathways via the kidneys, liver (bile), and intestines [4]