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Three changes distinguish it from the native fragment: a lactam bridge between the Asp5 side-chain carboxyl and the Lys10 side-chain amine, inversion to D-phenylalanine at position 7, and norleucine in place of the oxidation-prone methionine at position 4

doi.org/10.1155/2016/9537632 Showell MG, Mackenzie-Proctor R, Jordan V, Hodgson R, Farquhar C

Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines

Some people notice improved digestive regularity during this phase

14 CD31+ cells were also increased in the exendin-4 mice which suggested enhanced endothelial cell proliferation