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CVS's announcement didn't spell out formulary tier/copay
Understand the GLP-1 category context
In the LEADER (liraglutide) and SUSTAIN-6 (semaglutide) trials [2, 3], the GLP-1RAs rapidly and greatly decreased HbA 1c levels compared to placebo, which may have partly contributed to the increased incidence of diabetic retinopathy complications observed in SUSTAIN-6 (HR: 1.76 [95% CI 1.11, 2.78])
Patients may experience: Nausea and upset stomach (sometimes severe enough to cause vomiting) Constipation from slowed gastric processes To mitigate these unpleasant symptoms, I often tell my patients: Dont try to out-eat the medication
A liraglutide closely related to the semaglutide found in Wegovy and Saxenda didnt deliver quite the same bang for the buck
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