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(Summarises tirzepatide as a once-weekly dual GIP/GLP-1 receptor agonist with a long half-life, metabolised and excreted as metabolites in urine and faeces.)
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Tirzepatide attenuates binge-like drinking in male and female mice with dose- response effects similar to semaglutide Given that binge-like alcohol consumption is a clinically relevant concern (41), we tested whether tirzepatide affects this drinking phenotype in male and female mice using the DID paradigm
Some compounded semaglutide options are marketed as cheaper alternatives but are not FDA-approved and may carry safety risks
