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Finally, the safety results were consistent with the known safety profiles of both bimagrumab and semaglutide, with no new safety signals during the extension treatment period
Moving forward, the results of the phase 3 SURPASS clinical trial program demonstrated that tirzepatide was as effective and safe as other anti-diabetic agents, such as semaglutide and dulaglutide (SURPASS-2) (SURPASS J-mono), long-acting insulin analogs (degludec and glargine) (SURPASS-3,4), and placebo (SURPASS-1) (SURPASS-5), in managing T2DM diabetes [65,66,67,68,69]
What we found is something supplement companies often overlook
In the absence of robust, high-quality evidence, clinical decisions should be guided by individual risk assessment and shared decision-making
Our results also raise the question of what aspect(s) of ER functional capacity are altered by TCA cycle activity and glutathione redox
