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One of the pivotal mechanisms through which chronic alcohol use leads to depressive symptoms is neuroinflammation, a complex biological response characterized by the activation of glial cells, the release of pro-inflammatory cytokines, and the disruption of neuronal function

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Grossman E

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Furthermore, it is unclear whether this entity represents a distinct medical condition or acts as a substitute for a combination of risk factors that contribute to an individuals vulnerability to a particular ailment

These findings provide new insights into the cellular mechanisms by which EtOH exposure disrupts normal hepatic lipid catabolism