NAD+ is crucial for mitochondrial energy production, it serves as the cofactor for the Krebs cycle and oxidative phosphorylation, the cells ways of producing ATP
It may also affect anti-inflammatory signalling and extracellular matrix regulation
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* Percent Daily Reference Intakes (RI) are based on a 2,000 calorie diet
This barrier dysfunction contributes to the inflammatory cycle because substances that penetrate the compromised barrier trigger additional immune activation