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While this is unlikely to make the medication not work, it might lead to a slight increase in initial side effects for very sensitive individuals

In the first weeks on a new dose, most people eat significantly less than they did before, often without fully realizing how large the reduction is

This delay is because the gut is involved and the hepatic loop takes 3 - 48 hours to cycle through your portal vein, liver, bile, small intestine and ilium

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These side effects will likely begin to taper off once your body has adjusted to the medication via the recommended titration schedule

& Karpyak, V.M