However, if you desire more weight loss, you may need longer than 6 months
The SURMOUNT-4 trial, which studied patients who stopped tirzepatide after achieving weight loss, found that lipid parameters regressed toward baseline within 17 weeks of discontinuation
A landmark trial published in the New England Journal of Medicine found that participants using tirzepatide lost up to 20.9% of their body weight over 72 weeks, with results improving at higher doses across all treatment groups (Jastreboff et al., NEJM, 2022, North Carolina residents across the state, from Asheville to Wilmington, have real, practical access to tirzepatide today
GIP receptor activation has been used to enhance the therapeutic effects of GLP-1 agonists
Some patients notice appetite changes within the first few weeks, while weight changes may occur more gradually
These conditions may have soft tissue components that respond to treatment, but the underlying structural issues persist