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For example, many patients in dedicated HF studies do not have diabetes and, depending on the study, have either HFrEF or HFpEF (Fig
The cellular metabolic mechanisms of ferroptosis are illustrated in Figure 1
Brain 147 , 1225 (2024)
Complement degradation products such as C3a and C5a released by complement system activation can also indirectly enhance ferroptosis sensitivity by promoting iron ion efflux and lipid peroxidation, further expanding the regulatory dimension of inflammation on the cell death network
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