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The dual agonism of tirzepatide produces more pronounced appetite suppression and faster weight loss, which can lead to a more dramatic caloric deficit and potentially more acute fatigue during the initial adjustment period
Anisimov VN, et al
This is primarily to reduce the likelihood of gastrointestinal discomfort rather than to enhance absorption, and is consistent with the administration advice in the levocarnitine Summary of Product Characteristics (SmPC)
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