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And thats the only study

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Freeze lyophilized: yes (at -20C for extended storage)

H., Leppert, M

The limitation of that study was the small number of patients, but the authors concluded that compared with healthy neonates, the HIE group had increased melatonin, SOD, and NO concentrations, and the combination of melatonin to therapeutic hypothermia in infants with HIE can improve neurodevelopmental outcome at 6 months of age with effective effects in reducing oxidative stress in terms of NO and SOD serum level reduction

I know our first inclination is often to panic call every doctor we know and google until the cows come home