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Whilst a single instance of minor dose reduction is unlikely to significantly impact glycaemic control, consistent under-dosing over multiple injections could potentially reduce the medication's effectiveness
Achieve up to 20% body weight reduction with Wegovy and you may also see improvements in the following: In the STEP 1 trial, people using Wegovy saw greater reductions in systolic blood pressure compared to those on placebo with an average drop of 6.2 mmHg vs 1.1 mmHg. Treatment with Wegovy led to greater improvements in cholesterol measures, including reductions in total cholesterol, LDL ("bad" cholesterol), and triglycerides. By supporting weight loss and improving key health markers including waist circumference with a 5.7-inch (14.5cm) reduction vs 2-inch (5cm) reduction with placebo
This means doing more physical activity and changing their diet, along with using tirzepatide, to get better health outcomes related to heart failure
Express Scripts defines medical necessity in its prior authorization criteria (the BMI thresholds, step therapy requirements, and comorbidity documentation described above)
doi: 10.1016/j.meegid.2018.02.017 54 FlochP.MgraudF.LehoursP