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Based on the obtained results, the plasma concentration of semaglutide increased, reached maximum concentrations in 312 h, and decreased with an average t1/2 of 7.228.99 h

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Saxenda (liraglutide) Summary of Product Characteristics

Generation 4 (G4) polyamidoamine (PAMAM) dendrimers multivalently decorated with GLP-1 mimetics exhibit a 15-fold increase in receptor avidity compared to monomeric peptides and can co-deliver a C-X-C motif chemokine receptor 4 (CXCR4) antagonist [178]