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Long-Term Results : Patients using GLP-1 medications like Semaglutide or Tirzepatide often achieve 10-20% body weight reduction over the course of 6 months to 1 year , depending on individual factors like adherence to the medication, diet, and activity levels

This broader platform strategy may create additional long-term optionality and commercial flexibility as the obesity treatment market continues evolving

Growing body of evidence suggests that dysfunction of the GLP-1 pathway, which directly targets mitochondria and preserves mitochondrial functions, contributes to the pathophysiology of depression [86]

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