Postoperative changes Experimental findings indicate that following bariatric surgery, such as RYGB, ghrelin levels decrease significantly in the short term, with reductions exceeding 50% within the first two weeks
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This results in vasocongestion (blood flow to the genitals), effectively addressing ED and supporting sexual urge
Fatigue, irritability, brain fog, and low motivation are often seen as just stress or burnout. But in many cases, these symptoms may point to something deeper: a hormonal imbalance that affects how you think, feel, and function every day
The headline On Thursday 21 May 2026, Eli Lilly announced that participants in TRIUMPH-1, the first Phase 3 trial of retatrutide in obesity, lost an average of 28.3% of their body weight at 80 weeks on the 12 mg dose, with 45.3% losing at least 30% of their starting weight [1]
In clinical trials, about 11% of people taking Wegovy reported feeling fatigued or weak, more than double reported by the placebo group