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According to the Mayo Clinic, one of the most common medical uses of B-12 shots is for pernicious anemia

At the onset of the protocol, the MMN of patients was significantly impaired compared to sex- and age- matched healthy controls ( p =0.003), without any evidence of concomitant P300 component deficits

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Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D (2008) Hypothalamic IKK/NF-B and ER stress link overnutrition to energy imbalance and obesity

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