lower extremities, 3.4-fold
Importantly for older adults with polypharmacy, absorption of other drugs may be impacted by delayed gastric emptying and gastrointestinal side effects, namely vomiting, associated with GLP-1 receptor agonists [91]
Pregnancy, Breastfeeding, and Fertility Considerations GLP-1 medications are not approved for use during pregnancy, and most clinical guidelines recommend discontinuation at least 2-3 months before attempting conception
Veiga-Matos J, Remio F, Motales A (2020) Pharmacokinetics and toxicokinetics roles of membrane transporters at kidney level
The short answer: You can begin with your primary care clinician, a specialist in obesity medicine, or in some cases a telehealth provider
W.BayrerJ