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Zepbound was approved by the FDA for obesity, in late 2023
Andersen JM, et al
The hunger effect is dramatically reduced or absent
5 Pharmacological effects of GIP, GLP-1 and their mimetics The pharmacological benefits of GIP, GLP-1, and their synthetic mimetics arise from their pleiotropic effects, encompassing at least five key functions: bolstering insulin secretion and survival of pancreatic -cells and modulating glucagon release by the pancreatic -cells in response to glycemic levels, acting on the satiety center in brain, slowing gastric emptying, regulating lipid and glucose metabolism through effects on adipose tissue and liver, and reducing systemic blood pressure
This is why many people hit weight loss plateaus, even when sticking to a strict diet
Since 12/31/2023, LLY has surged roughly 66%, while NVO has fallen about 61%, a spread of nearly 128%
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