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This leads to covalent binding of NAPQI to cellular proteins, triggering mitochondrial dysfunction, oxidative stress, and ultimately, regulated forms of cell death as ferroptosis (Kim et al

47 , e149 (2015)

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Tetramethyl bisphenol A, a bisphenol analog, is used as a fire retardant, and it inhibits testosterone synthesis in late puberty by inducing ferroptosis in Leydig cells [112]