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Similarly, decreased miR-19a expression in gefitinib-resistant NSCLC cell lines contributes to cell migration, EMT, and gefitinib resistance by negatively regulating c-Met expression and blocking its downstream pathways (such as PI3K-AKT and RAS-ERK pathways) (Cao et al., 2018)
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The absorption factor could have some bearing but weight loss is likely to be the bigger reason, he adds
Cuprizone-induced demyelination in the rat cerebral cortex and thyroid hormone effects on cortical remyelination
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