Borderline deviation from HardyWeinberg Equilibrium was observed for CYP2D6*10 in the Singapore cohort, which could be attributed to the *36-*10 genotype (not analyzed) 54 and/or population admixture (17% Malays/Indians vs 83% Chinese)
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This degree of improvement has significant implications for preventing progression to more serious liver conditions including cirrhosis and liver cancer
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GPER holds promise for energy balance and weight management by regulating energy expenditure and thermogenesis