Glutathione is like a rechargeable battery
Thus, we cannot conclude that the improved health of the animals correlates with increased levels of GLP-1 in vivo and will likely need to move to a larger animal model to address this question
Will they have to be taken for the remaining 50-plus years of someone's life
For instance, some studies have found that GLP-1RAs can cause or exacerbate muscle atrophy, leading to a decrease in muscle mass, this contradicts the hypothesis that GLP-1RAs have therapeutic potential in SIM (181,182)
In addition, GLP-1 is a strong inhibitor of glucagon secretion
Overview of the study design It was a prospective, randomized, parallel-group, comparative, open-label clinical study