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Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration

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Ensure it is securely in place

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Further analysis of the DEGs showed that the combination group had a significantly greater overlap with the control group than the single-drug groups did (Fig