PMC 7519826
Key Background Novo Nordisk was the first major pharmaceutical company to bring a GLP-1 to market with Wegovy in 2021
232 A study involving multiple sclerosis patients in Saudi Arabia noted that low B12 levels were correlated with low T3 and T4 levels

In this episode: How to look and feel good in your own skin Why a manicure can be as good as meditation The importance of making friends with your reflection Ways to talk to a teen with self-image insecurities What really gets rid of spots? The key ingredients to look for in skincare Where to go for great eyebrows The tweakments worth splashing out on Midlife haircare hacks, from covering greys to adding volume Links mentioned in the episode: Acnecide cream for spots Paulas Choice BHA products with salicylic acid Azelaic acid Skin + Me products Dermatica skin treatments Olaplex haircare K18 haircare Living Proof haircare Josh Wood hair gloss Glaze hair gloss Sam McKnight hair texture mist Color Wow Root Cover Up MD London Backcombing Brush CeraVe skincare Polynucleotides: a guide JULINE skin treatment Blink Brow Bar Shavata Singh Brows & Lashes Hollie Parkes brow expert More from Sarah: Follow Sarah on Instagram Read Sarahs book, Diary of a Beauty EditorGet in touch with a question for Liz: Email: [email protected] WhatsApp: 07518 471 846More from Liz: How To Age A Better Second Half Follow Liz on Instagram Follow Liz Earle Wellbeing on InstagramHost: Liz EarleProducer: Anouszka Tate (Fresh Air Production) Content Writer: Lucy ParleyHead of Brand: Ellie SmithSome links may be affiliate links, which help support the show at no extra cost to you

The Melanocortin System Explained The melanocortin system is a complex neuroendocrine network that regulates multiple physiological processes, including: Sexual desire and arousal Erectile function Appetite and energy balance Skin pigmentation Blood pressure regulation Melanocortin receptors, particularly MC3R and MC4R, are highly expressed in the hypothalamus and central nervous system
In research settings, it has been referenced in the scientific literature for structural and biochemical characterization, as well as investigations involving gene expression, cellular regulation, and various in vitro and animal models