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Notably, FOXO4-DRI treatment did not cause significant changes in body weight or testis weight, suggesting a targeted effect [1]

Therefore, the levels of cytokines (IL-6, IL-12, TNF-) in the macrophage supernatant were detected using an ELISA assay (Fig

In addition, the increased expression and activity of NOX and xanthine oxidase and NOS becoming uncoupled and structurally unstable also lead to increased ROS production [8]